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The Bottom Line GLP-1 receptor agonist medications are changing lives for many people, but they also change the way the digestive system works and, for many users, reduce the dietary fiber and nutrient diversity that a healthy gut microbiome depends on

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Early detection and treatment of a B12 deficiency are important

Mounjaro ranked second, prescribed to nearly 1% of adults, followed closely by Wegovy, Zepbound, and Saxenda together at around 0.7%

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B.MohammedA.BryantT.ZhangY.BrewerM.DuffA.et al (2016)