The most well-known example of this in GLP-1r signaling was the failure of Taspoglutide in clinical trials
10.1007/s00401-012-1038-9 Acta Neuropathol
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Informacin sobre uso y prescripcin de Ozempic (semaglutida) Ozempic es un medicamento destinado al tratamiento de la diabetes tipo 2 en personas adultas, que acta regulando los niveles de glucosa en sangre
Importantly, aspiration events were identified using ICD codes in some studies, while other studies did not clearly define the method of identifying aspiration, introducing variability in outcome assessment