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Acknowledgements The authors wish to thank Dr Nasrin Shokrpour at the Research Consultation Center (RCC) of Shiraz University of Medical Sciences for her invaluable assistance in editing this manuscript

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Observations point towards the aggregation of certain autoantigens, encompassing both cholesterol and phospholipids, within the compromised dermal regions

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If nausea persists during dose increases, your healthcare provider might adjust your plan by extending the current dose for an additional 2-4 weeks, pausing further increases until symptoms improve, or temporarily lowering the dose