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Moreover, Genistein, by reduction of pro-inflammatory mediators (IL-6, tumor necrosis factor- (TNF-) and C-reactive protein (CRP)) in serum and intestine in alloxan-induced diabetic rats, reduces the damage of L-cells and leads to an increase in the expression and secretion of GLP-1[191]

Sterile corncob was used as bedding material and changed every day

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The non-inferiority design requires a smaller study participant sample and a shorter observation period