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[DOI] [PMC free article] [PubMed] [Google Scholar] 14.Tsamesidis I., Reybier K., Marchetti G., Pau M.C., Virdis P., Fozza C., Nepveu F., Low P.S., Turrini F.M., Pantaleo A

doi: 10.2139/ssrn.3646583 69 VajaR.ChanJ

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Another TKI, gefitinib (ZD1839, Iressa), which targets the epidermal growth factor receptor (EGFR), has been shown to restrict M.tb replication in both macrophages as well as in the lungs of M.tb -infected mice by promoting the host autophagy pathway through the inhibition of the p38 MAPK signaling pathway activated by EGFR [10]

Because this version delivers double the strength of the standard 600mg option, practitioners often choose it for patients seeking a more pronounced brightening effect or continuing an established treatment plan