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Description

Our animal models, induced using endothelin-1 (ET-1), reflect clinically relevant cerebral I/R conditions yet may not fully capture the complexity of human pathophysiology, including inter-individual anatomical variation and comorbidities ( in vivo , including their potential off-target effects and clearance pathways

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The downregulation of Thoc5 induced by LPS was restored in the offspring of resveratrol-treated mice and brought a significative reduction of pro-inflammatory cytokines in the placenta and fetal brain

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The gut microbiome and the brain are intricately connected

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doi: 10.1007/s00438-018-1517-3 34 MrowickaMagorzataMrowickiJDraganGMajsterekI

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