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24,25 Leptin responsive neurons in the ARC include those containing the agouti-related peptide (AgRP) and orexigenic peptides neuropeptide Y (NPY), and those containing the anorexigenic peptides -melanocyte-stimulating hormone (-MSH) and cocaine and amphetamine-regulated transcript (CART)

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Thiamine has been suggested to have a beneficial effect in the treatment of AD, but further investigation is needed to determine its efficacy [75]

But the effect of the natural GLP-1 only lasts seconds to minutes, while the prescription GLP-1 medications remain active for days, so it's a whole different concentration and duration, Dr