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He pointed to retention as the real issue GLP-1s are weekly injections, and stopping means the weight comes back

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(1998), ipamorelin activates the growth hormone secretagogue receptor (GHS-R1a) on pituitary somatotrophs without significantly stimulating ACTH, cortisol, prolactin, or aldosterone secretion a selectivity profile not achieved by earlier GHRPs including GHRP-2, GHRP-6, or hexarelin