"DSM in Food, Beverages & Dietary Supplements"
Sickle RBCs have a decreased NAD redox potential, demonstrated by a reduced ratio of NADH to total NAD (NAD + plus NADH) when compared to normal RBCs
In a retrospective study wherein BMI was used as a proxy for adiposity (median age 40 yr, range 2077 yr, median BMI 26 kg/m2, range 18.349.8 kg/m2), total and pulsatile 24 hour GH secretion were both negatively associated with BMI, and GH secretion was higher in women than men below 50 years of age, likely due to the influence of estradiol levels on IGF-1 levels (22) (Figures 3,4)
Klaue, K., Garmshausen, Y
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This highlights the importance of personalized approaches to supplementation and the role of individual health status