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A dominant-negative Gs (DNGs) was generated 3 by introducing eight mutations: S54N, G226A, E268A, N271K, K274D, R280K, T284D, and I285T

Statistical analysis Data are presented as mean SD

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Lixisenatide is also a short-acting GLP-1 receptor agonist based on the structure of exendin-4 with a half-life of approximately 3 hours [22]

While these might seem like minor technical changes, they have significant implications for supplement testing

Vascular protection and anti-inflammatory effects Emerging evidence suggests that GLP-1RAs hold considerable therapeutic promise in ophthalmic pathologies, particularly through their vasoprotective and anti-inflammatory mechanisms