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Another group deployed a causal inference approach accounting for the competing risk of death in emulated clinical trials and showed that metformin use is associated with a lower hazard of all-cause mortality and a lower hazard of dementia onset, relative to sulfonylureas, another anti-diabetic drug (Charpignon et al., 2022)

Sterile water contains no preservative and is only safe for single-use once a vial is accessed, it should be used entirely to avoid contamination

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