This is the question most people actually type into Google, so let's settle it properly instead of dodging it
Al Musaimi O, Lombardi L, Williams DR, Albericio F
R 3 is H, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, optionally substituted C 3 -C 6 cycloalkyl, optionally substituted C 2 -C 7 heterocycloalkyl, optionally substituted C 6 -C 10 aryl, optionally substituted C 3 -C 9 heteroaryl, OR 6 , NR 5 R 6 , C(O)R 7 , -0O 2 R 6 , C(O)NR 5 R 6 , N(R 5 )C(O)R 7 , N(R 5 )CO 2 R 7 , NHS(O) 2 R 7 , S(O) 2 NR 5 R 6 , or R 2 and R 3 together form an optionally substituted C 2 -C 7 heterocycloalkyl ring
Bioavailability was optimized
In summary, after consideration of the public comments we received, we are finalizing our proposal with modification and reassigning CPT code 0712T to APC 5722 (Level 2 Diagnostic tests)
Wuhan-Hu-1 was specifically chosen to be expressed in the vaccine after the group reported that strain-specific mutations adversely altered the antigen structure, stability and immunogenicity [135]
