(PubMed) O'Gara EA, Hill DJ, Maslin DJ
Both studies administered B12 i.m., one used methyl-B12 at a dose of 500 g three times per week for 2 weeks, 63 the other used cyano-B12, 1000 g daily for 2 weeks
Don Colbert, M.D
2 Oxidative stress and periodontitis 2.1 Basic concepts of oxidative stress Oxidative stress refers to an imbalance between the production of reactive oxygen types (involving superoxide anions, hydrogen peroxide, etc.) and other oxidants in the cellular and extracellular environment, capable of damaging cell structures and functions ( Under normal conditions, the body regulates and neutralizes these parlous oxidants by antioxidant systems (including superoxide dismutase, glutathione peroxidase, etc.), remaining redox balance within cells ( 2.2 Relationship between oxidative stress and gingival tissue inflammation Oxidative stress is very vital in the progress of periodontitis, tightly linked with inflammation of the gingival tissues
Solutions were vortexed for 10 min, centrifuged at 4000 rpm for 10 min and supernatant transferred to quartz cuvette
doi:10.3389/fimmu.2021.729539