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Take 500 to 1,000 mg at the first sign of symptoms

Copyright 2026 PhysioPod UK Ltd Regional healthcare pathways, including the latest lipoedema guidelines published by NHS Wales, explicitly recommend the use of hand-held massagers to stimulate circulation, improve tissue oxygenation, and reduce inflammation (Lymphoedema Wales Clinical Network, 2025)

In extreme cases, thiamine deficiency can cause neuronal death due to lack of cellular energy from impaired ATP production

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