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Cleveland Clinic describes GLP-1 agonists as a class of medications that mainly help manage blood sugar levels for people with T2D, but notes that due to the drugs satiety effect, they can often promote weight loss

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However, these studies were not specifically designed to assess bone health as a primary outcome

Using fatty acids to prolong the duration of the action of peptides and proteins was already a long established technique at Novo Nordisk and elsewhere and had been successfully applied to insulin (insulin detemir) (Knudsen, Lau)

Based on collective human data, a glycemic threshold of 99 108 mg/dL may exist, below which GIP primarily exerts glucagonotropic actions (35)

Now heart health experts believe these medications can provide a robust benefit to heart health