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The pharmacokinetic profile supports once-weekly dosing, with a half-life of approximately five days

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Yes, many clinicians transition patients between the two when weight loss plateaus, side effects become intolerable or supply issues arise

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More data are needed to clarify the effects of GLP-1RAs on the incidence of OA, RA, PsA and axSpA, as well as on disease activity and progression in these conditions

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