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Further development of TGR-based therapeutic approaches is impeded by the lack of non-covalent small molecule inhibitors of TGR, a well-known and general problem for all the members of the high molecular weight, Sec-containing TrxR subfamily that are considered attractive and unexploited drug targets for several human diseases 21,22

Nature , 432(7016), 640645

Jun Feng, University of Wisconsin-Madison, United States Updates Copyright 2021 Saini, Kashyap, Bindal, Saini and Gupta

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