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FIGURE 2 Multiple RCTs, in more than 3,700 IBS-D or IBS-M patients, have demonstrated that alosetron significantly reduces abdominal pain and improves stool consistency compared to placebo (Table 4)

doi: 10.3892/etm.2018.5719 113 LeeH-SLimW-CLeeS-JLeeS-HLeeJ-HChoH-Y

It isn't known whether this risk applies to humans

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On 30 September 2022, the Department of Health and Social Care (DHSC) issued Medicine Supply Notifications (MSNs) advising health professionals not to initiate new patients on Ozempic (semaglutide injection) and Trulicity (dulaglutide injection), to ensure that Ozempic is only used for licensed indications