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Why does this research matter

, Melanocortin 1 receptor attenuates early brain injury following subarachnoid hemorrhage by controlling mitochondrial metabolism via AMPK/SIRT1/PGC-1 pathway in rats, Ivyspring International Publisher, 2021

2017 Dec 19;8(12):398

The treatment reduces melanin production and lightens pigmentation

It includes 25P/28P/29P mutations to reduce the proteins propensity to form fibrils and -sheets and the insertion of a C-terminal proline improves binding to the CTR channel