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A 12-week clinical trial showed subjects taking AOD-9604 (1 mg/d) lost an average of 2.6 kg, compared to 0.8 kg in the placebo group.

Once reconstituted, hold the solution at 2-8C, and prepare single-use aliquots at -20C for anything beyond short-term use

Methods Study design and data source This large, population-based, retrospective cohort study was conducted using the TriNetX research network (Cambridge, MA, USA)

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In summary, although an aberrant GLP-1R presented an agonist-independent functionality as the siRNA data suggest, an agonist-dependent functionality cannot be discarded