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Analysis of GSSSSG generation Ferric cyt c (400 M) or ABTS (400 M) was mixed with GSSSG or GS 34 SSG (400 M), NADPH (400 M) and GR (1 U ml 1 ) in a total volume of 100 l in PBS

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Treatment with a combination of sodium nitrite, amyl nitrite and sodium thiosulphate was reported in 74 patients, with results indistinguishable from those of hydroxocobalamin and sodium thiosulphate

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Prolonged homeostatic disruption impairs protein degradation processes, weakens molecular chaperone capacity, fosters inflammation, and incites mitochondrial damage through ROS/Ca 2+ , potentially affecting the follicular microenvironment and oocyte developmental potential [332, 333]