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Kurtzhals, P., Flindt Kreiner, F., & Singh Bindra, R

Compared with conventional GLP-1 receptor agonists, such as liraglutide and semaglutide, tirzepatide has demonstrated superior efficacy in body weight control in several phase III clinical trials, with average weight reductions exceeding 20% in some study populations (15)

Reinehr T, Hebebrand J, Friedel S, et al

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Hypoglycemia risk (when combined with insulin or sulfonylureas)less common with Semaglutide monotherapy due to glucose-dependent mechanism [3]

Barale C, Buracco S, Cavalot F, Frascaroli C, Guerrasio A, Russo I: Glucagon-like peptide 1-related peptides increase nitric oxide effects to reduce platelet activation