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Cell Metabolism, 34(9), 12341247
Chichester: John Wiley & Sons
Patients with stage 1 or stage 2 hypertension see larger absolute BP reductions than normotensive patients
Depending on the response, the dose may be increased to 12.5mg for weeks 17 to 20, and then to 15mg starting from week 21
Some people are unable to tolerate the drugs because of their side effects, particularly severe nausea and diarrheaa 2021 study showed 4.5 percent of people taking semaglutide discontinued the drug because of gastrointestinal issues
24,25 Treatment can also reduce lipid storage to protect against the development of fatty liver disease by inhibiting fatty acid synthesis and promoting fatty acid oxidation
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