Of these, only seven produced 50% solubility (SMPX_HUMAN, HBP1_HUMAN, IPKA_HUMAN), the others were either present in very low amounts (MAR1_HUMAN, APR_HUMAN) or were not solubilized at all (STP1_HUMAN, BTG1_HUMAN, MGN_HUMAN) [64, 65]
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For instance, a nucleolar localization signal (NoLS) was used for nucleoli, [34,35] while protein markers such as G3BP1, Dcp1b, Coilin, and PSPC1 were employed for stress granules, [36] p-bodies, [37] Cajal bodies, and paraspeckles, [38,39] respectively
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Some observational studies in elderly people have also found that lower blood levels of vitamin C or vitamin E to be associated with poorer performance on cognitive tests of memory (109, 113, 114)