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The production of NO by NOS2 (in micromolar amounts) is much higher and more sustained than by other NOSes, thereby making NOS2 an important player in regulating inflammation and infection (28, 32)

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Other clinical findings include respiratory depression, nausea, vomiting, diarrhoea, hypothermia or fever, hypotension, tachycardia, miosis, agitation, hallucinations, tremors, myoclonus and seizures

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That is more than the entire rest of the cognitive-peptide shelf combined