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[PUBMED Abstract] McMeniman EK, Duffy DL, Jagirdar K, et al.: The interplay of sun damage and genetic risk in Australian multiple and single primary melanoma cases and controls

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Cell and animal studies support effects on mitochondrial respiration, fatty-acid oxidation, oxidative muscle features, energy expenditure, and exercise endurance

It is important to note that some vitamins can be toxic if given when not necessary or in excess

Low SAM may limit methyl-donor reserve and could interfere with SAM-dependent creatine synthesis

The frequency depends on individual needs and recommendations by a healthcare provider