This is a genuine, actively debated caveat rather than a settled harm, and it is reported here neutrally
Lycopene is significantly more bioavailable from cooked or processed tomatoes than raw, with tomato paste, passata, and canned tomatoes providing more absorbable lycopene than fresh tomatoes
Circ Res 93:354363 Shi F, Wang YC, Zhao TZ, Zhang S, Du TY, Yang CB, Li YH, Sun XQ (2012) Effects of simulated microgravity on human umbilical vein endothelial cell angiogenesis and role of the PI3K-Akt-eNOS signal pathway
This includes understanding weekly protocols, calculating the correct volume, and following administration tips
Penetration of microplastics and nanoparticles through skin: effects of Size, Shape, and surface chemistry
The result is better absorption with zero stomach distress no loose stools, no cramping, just results