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The results of long COVID investigations cautiously suggest that impaired metabolism and neuronal dysfunction may play a role in mental fatigue, similar to hypotheses for ME/CFS

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GHK-Cu concentrations in human plasma decline with age: approximately 200 ng/mL at age 20, dropping to 80 ng/mL by age 60

Fair quality of methodology was considered in studies that enrolled only male subjects (population category) [14, 22, 25, 26, 28] or when blood sampling did not coincide with a steady state of an investigated drug [13,14,15,16,17, 19, 24]