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It is a miracle drug." GLP-1 agonist drugs, like Ozempic, Wegovy, Mounjaro and Zepbound, can help with weight loss by mimicking at least one hormone produced by the gut to signal fullness, which leads to a reduced appetite

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In addition, incretin enthusiasts had suffered a serious disappointment, when it was observed, at about the same time, that GIP although being potently insulinotropic in healthy individuals was ineffective in patients with type 2 diabetes (58)