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Increased fat synthesis based on enhanced glycolytic activity (pklr1, sterol regulatory element-binding protein-1 [SREBP1c], fas, and liver X receptor a [lxra]) in aged mice partly accounted for hepatic steatosis (increased leukocytic infiltration) and necrosis (increased plasma aspartate aminotransferase [AST] activity), compared with reduced srebp1c and fas mRNA levels in young mice

An older type of heparin is best administered by a constant intravenous infusion

Blood pressure typically decreases with both peptides, likely due to weight loss and improved insulin sensitivity rather than direct vascular effects

Nearly all public and private insurance plans cover Ozempic for Type 2 diabetes

Some patients benefit from addressing the psychological and emotional components of sweet cravings

Reference: Gwyer D, Wragg NM, Wilson SL (2019)