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After years of blockbuster injectable drugs dominating headlines, and medicine cabinets, the obesity pharmacotherapy landscape is being flipped on its head by a new class of pill-based GLP-1 treatments

However, it is currently unclear and to what extent the differences observed in CVOT reflect the heterogeneous pharmacological properties of each drug in the GLP-1RA category

For effectiveness, opinions are divided

Compounded GLP-1 Therapies It is important to distinguish between FDA-approved medications and compounded formulations

It should also be noted that in recent large-scale clinical trials there were signs of good treatment potential for GLP-1RAs in osteoarthritis (OA) [13, 14]

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