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Semaglutide has already demonstrated cardiovascular benefits in the SUSTAIN and SELECT trials, giving it an established safety profile for cardiovascular risk reduction

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Additionally, we tested whether the time between sample collection and deproteinization impacted plasma GSH in its various forms (total GSH, free GSH, GSSG, and the ratio of free GSH to GSSG) in heparinized and EDTA-treated plasma samples

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In both cases, trialists responded positively to new results reporting requirements, with NIH-funded trials reporting their results in greater than 50 percent of cases between 2008 and 2019, and industry funders reporting results in greater than 50 percent of cases between 2008 and 2018