Cartilage faces even greater obstacles given avascular nature (no blood vessels penetrating tissue), low cell density (chondrocytes sparse within extensive extracellular matrix), minimal metabolic activity (slow turnover and repair), and mechanical loading challenges (constant stress impeding healing)
Staresinic M, Sebecic B, Patrlj L, Jadrijevic S, Suknaic S, Perovic D, et al
The human body cant produce vitamin B6 naturally, so it needs to be obtained through diet or supplements
Acta Orthop
N = Icke-representativt underlag vilket kan ha olika orsaker, t ex osedvanligt stora prisfrndringar p.g.a
Additionally, conditions such as pernicious anemia, gastrointestinal disorders, or even aging can impair B12 absorption