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PIONEER 1: randomized clinical trial of the efficacy and safety of oral semaglutide monotherapy in comparison with placebo in patients with type 2 diabetes

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Lee JC, Kim SH, Oh YS, Kim JH, Lee SR, Chae HD

In dermatological contexts, the most clinically relevant gene targets include: COL1A1 and COL3A1 upregulation increases procollagen type I and III synthesis, directly counteracting age-related collagen depletion