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Request liver enzyme testing and, if available, fibroscan imaging to track improvement objectively

Ongoing research into nutritional and exercise interventions, as well as novel pharmacological agents such as myostatin/activin pathway inhibitors (243) or agents targeting the apelin pathway (244) holds promise for preserving lean mass and improving overall health in patients undergoing treatment with GLP-1 and dual GIP/GLP-1 receptor agonists

For example, insulin-sensitive MCs have been described 28,29,30 as have orexin-sensitive MCs projecting to the lateral hypothalamus 31

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There is also growing interest in whether GLP-1 medications may help with nicotine dependence, binge eating disorder, and other compulsive reward-driven behaviors, says Anton

PMID 24725840