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The deposition of acylcarnitine also disrupts the function of the Na + -K + -ATP pump and affects the action potentials, polarization, hyperpolarization, and depolarization cycles of the myocardial cell membrane, which further affects the electrophysiological stability of the heart [295]

doi: 10.1186/s13098-015-0018-3 13 GachonFLoizides-MangoldUPetrenkoVDibnerC

Mitochondrial KG can enter the mitochondrial TCA cycle, serving as a source of carbon, or can be transported to the cytosol by SLC25A11 transporter, exchanging KG for malate (Figure 1) [6,27,63,64]

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