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10.1161/STROKEAHA.115.008686 Stroke 9 ChuH.HuangC.DingH.DongJ.GaoZ.YangX.et al (2016)

For the majority of patients, gastrointestinal side effectsthe most common categorytypically peak during the first 48 weeks of treatment or following dose escalation, then gradually diminish over subsequent weeks as physiological adaptation occurs

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1 Tolerability Semaglutide is generally well tolerated with similar dropout rates when compared with placebo, although it may be less well tolerated than dulaglutide (Trulicity)