Standardized processes are required for clinical translation where manufacturing processes will be standardized
Gut microbiota impact on the peripheral immune response in non-alcoholic fatty liver disease related hepatocellular carcinoma
R., Fadel, P
Qu cambios ha observado en los pacientes que usan los medicamentos para perder peso GLP-1
The goal of the study was to ascertain whether GI adverse events (GI AEs), such as nausea/vomiting, diarrhea, constipation, and dyspepsia (indigestion), during the dose escalation phase (baseline to week 12) and from baseline to the end of treatment, are responsible for the greater weight loss seen with semaglutide compared to other GLP-1RAs
The gut releases a hormone called GLP-1 into the bloodstream GLP-1 travels to the pancreas and brain where it attaches to special GLP-1 receptors Carbohydrates turn into glucose (sugar) and enter the bloodstream, raising blood sugar The pancreas releases insulin to help cells use this sugar for energy Extra sugar gets stored as glycogen for later use, or as fat if theres too much The pancreas also releases amylin which slows down digestion to prevent blood sugar from spiking too fast The GLP-1 receptors: Stimulates insulin production only when blood sugar is elevated Suppresses glucagon (hormone that raises blood sugar) when not needed Slows gastric emptying (digestion) to prevent blood sugar spikes Reduces appetite and creates feelings of fullness In people with diabetes, this whole system doesnt work properly, leading to blood sugar levels that stay too high for too long
