While compounding may still be permitted in limited situations, such as when patient-specific needs cannot be met by FDA-approved products, access has narrowed, leaving medications like Mounjaro and Zepbound as the primary options for most patients
(One of my PhD advisors asked me, "what is the unique contribution of your work that others must know?" That's my mandate here.) The following story checks all these boxes
In May 2025, Septerna, Inc
The FDA has recently added oral semaglutide options, further broadening treatment possibilities
Recommended Dose: Take 2 capsules 2 times per day
In clinical trials, patients lost an average of 5% of their body weight (~10-12 lbs.) after 20 weeks and close to 15% (~30 lbs.) after 1 year on the highest 2.4 mg dose