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Hall ED, Wang JA, Bosken JM, Singh IN

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However, the structural similarity of these substitutes to BPA raises concerns about comparable or even enhanced endocrine-disrupting potential, particularly given their affinity for oestrogen receptors (ER, ER) [166, 169,170,171]

PT-141 was engineered for improved selectivity toward MC4R with reduced MC1R activity, eliminating the tanning effect while retaining central arousal pathway activity

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