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Nevertheless, although coronary calcium scores may have a predictive value regarding future cardiac events in asymptomatic subjects, it may not be a reliable marker of plaque burden in symptomatic patients (96, 97)

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### Conservative 24-Week Titration Protocol | Weeks | Weekly Dose | Notes | |-------|-------------|-------| | 14 | **1mg** | Starting dose

The cells were plated in DMEM containing 10% foetal bovine serum (FBS) and 5.5 mM glucose

199 Activated Akt promotes the expression and translocation of GLUT4 (Glucose Transporter Type 4) to the cell membrane, increasing cellular glucose uptake