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The tesofensine article covers a compound that approaches weight loss through neurotransmitter modulation, providing appetite suppression through a completely different mechanism than GLP-1 agonists

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Six Phase I/II clinical trials confirmed an excellent safety profile across approximately 900 participants

No significant differences between treatment groups were observed using the Chao1 richness estimate 42 , which accounts for ASV rareness in the richness measure (Supplementary Fig

It is possible that relevant scientific findings may have been reported since the completion of the review