Over time, it increases the risk of: Type 2 diabetes Fatty liver disease Cardiovascular conditions Many patients delay care because they assume hunger is normal
This positive inotropic effect is mediated by GLP-1R
"We know from the Diabetes Prevention Program that yes, if we improve weight without medication, if they're able to improve it by 5% to 7%, even that smaller amount of weight does improve people's different chronic conditions," Alexander explained
Bird GS, Burgess GM, Putney JW Jr
Gastrointestinal adverse events and weight reduction in people with type 2 diabetes treated with tirzepatide in the SURPASS clinical trials
Step three: while waiting for results, ensure adequate potassium and magnesium intake from food sources