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Exendin-4, glucagon-like peptide-1 receptor agonist, enhances isoflurane-induced preconditioning against myocardial infarction via caveolin-3 expression

Ma X, Liu Z, Ilyas I, Little PJ, Kamato D, Sahebka A, Chen Z, Luo S, Zheng X, Weng J, et al

This was solved once Collip found a way to remove contaminants from the extract

However, despite the lack of evidence, many doctors began prescribing GLP-1 medications off-label for their type 1 patients, especially those who also have obesity

Robust anti-obesity and metabolic effects of a dual GLP-1/glucagon receptor peptide agonist in rodents and non-human primates