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Choi et al., 2000) and with purified enzyme has been shown to also decrease the K M for glutamate (Huang et al., 1993)

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Mitochondrial dysfunction, including systemic deficiency of the electron transport chain complex I, is a well-established player in the pathogenesis of both sporadic and familial PD [96,97,98]

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Neuro-Endocrinol Lett 30:4629 Aboul-Fotouh S (2013) Coenzyme Q10 displays antidepressant-like activity with reduction of hippocampal oxidative/nitrosative DNA damage in chronically stressed rats