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We have reported that SCFAs metabolized by intestinal bacteria contribute to PCa growth by increasing systemic and prostate local IGF-1 productions, and revealed the gutprostate axis involving bacterial metabolites ( PTEN ) - knockout mice [ Pb -Cre+

Side effects are minimal, typically limited to mild injection site redness

If lupus flare symptoms emerge, dose escalation pauses until stability is confirmed

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PMCID: PMC5855430