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As this subgroup of ASD patients have several parallels with the rodent PPA model of ASD, 13 this rodent model may be a useful tool to further examine the temporal relation of behavioral bouts in relation to carnitine-acyl-carnitine fluctuations, and their possible response to therapeutic compounds thought to be useful in the treatment of ASD and mitochondrial dysfunction such as carnitine supplementation

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Pre-treatment with topical anesthesia may be required as well