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Alternatively, if the elevated anion gap persists despite cessation of acetaminophen and administration of N-acetylcysteine, pyroglutamic acidosis is unlikely, and an alternative diagnosis should be sought

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This risk increased progressively with a longer duration of discontinuation: 14% for 1 year and 22% for 2 years

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However, after the FDA authorized Wegovy for weight loss, there was such demand for the drug that providers turned to prescribing Ozempic when they couldnt get Wegovy