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Generative AI statement The authors declare that no Generative AI was used in the creation of this manuscript

Intravenous administration is not recommended, although in exceptional cases (such as extreme thrombocytopenia) cyanocobalamin may be administered by this route

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Remaining: 5.0 mg

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In the Sibutramine Cardiovascular Outcomes (SCOUT) trial, the drug was shown to be associated with increased risk of major adverse cardiovascular events (a composite of non-fatal heart attack, non-fatal stroke, resuscitation after cardiac arrest, and cardiovascular death) in obese patients, as compared to placebo [29]