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The later study compared cases to an adult reference range while noting that the paediatric range is lower

This inheritance pattern explains why some individuals are heterozygous while others are homozygous for MTHFR mutations

Editor information Editors and Affiliations Rights and permissions Copyright information 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG About this chapter Cite this chapter Hettiarachchi, P.V.K.S., Tilakaratne, W.M

Table 3 compares the four major renoprotective drug classes, namely GLP-1RAs, SGLT2 inhibitors, Aldosterone antagonists and RAAS inhibition (ACEi/ARB), all in the context of treating albuminuria due to diabetic kidney disease

In the United States, although men have higher age-adjusted mortality rates for 8 of the 10 leading causes of death, AD is a notable exception: women experience higher prevalence and AD-specific mortality, making it the only major cause of death more common in women ( Today, nearly two-thirds of patients receiving medical care for AD are women

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